The Lu group's interests lie at the interface between chemistry and biology. We are developing innovative chemical approaches to provide deeper insight into biological structures and functions. We are also taking advantage of recently developed biological tools to advance many areas in chemistry, such as inorganic chemistry, chemical biology, analytial chemistry, and materials chemistry. We strive to make significant contributions in three principal areas of research:
  1. Biosynthetic Inorganic Chemistry and its application in environmentally benign catalysis in renewable energy generation and pharmaceuticals.
  2. Fundamentals of DNAzymes and Sensor Development for environmental monitoring and medical diagnostics.
  3. Functional DNA Nanotechnology: Precise Spatial and Dynamic Controls of Nanomaterials Assembly and its Applications in Sensing, Imaging and Medicine.
Recent News
2015 04 05 | Fellowship Awarded to Recent Lu Lab Graduate | Congratulations to recently-graduated lab member Ambika Bhagi-Damodaran for being awarded the Faculty for the Future Fellowship from the Schlumberger Foundation for the 2016-2017 academic year.
2015 12 02 | Chemists Acheive Wider-Than-Ever Redox Range | Work by Parisa Hosseinzadeh and others in the Lu group has been highlighted by C&EN and given a commentary by PNAS for the successful engineering of the entire physiological redox range into a single protein scaffold, azurin.
2015 11 24 | Having Biomarkers at the Fingertips | A recent publication by JingJing Zhang, et al, has been highlighted in Angewandte Chemie for their work to expand the utility of the common glucose meter.
2015 10 18 | Dr. Lu has been selected for the prestigious Thomson Reuters 2015 list of Highly Cited Researchers. Highly Cited Researchers 2015 identifies the world’s most influential contemporary researchers across 21 scientific fields. Over three thousand researchers earned the distinction by writing the greatest numbers of reports officially designated by Essential Science Indicators (ESI) as Highly Cited Papers—ranking among the top 1% most cited for their subject field and year of publication, earning them the mark of exceptional impact. A summary of seven UIUC faculty on the list may be found here.
2015 09 21 | Designed Enzyme on Par with the Natives | C&EN has highlighted recent work by the Lu group and collaborators to engineer a myoglobin mutant with oxidase activity nearly that of native CcO by increasing the rate of electron transfer from cytochorm b5. The article may be found here.
2015 08 21 | Dr. Lu has participated in a Mesoscale Chemistry Workshop, organized by the National Academies of Sciences. Here is a summary of the workshop in which Lu group research has been presented.
2015 June | Dr. Lu has been honored as a Fellow of the Royal Society of Chemistry (FRSC).
2015 May | Two Lu group members, Li Huey Tan and Shiliang Tian, have been awarded the Prof. Walter G. Klemperer and Stan Piper awards, respectively, for the best PhD theses in materials and inorganichemistry. Congratulations!
2015 May | Yi Lu has been named the recipient of the 2015 Royal Society of Chemistry Applied Inorganic Chemistry Award for research on the catalytic activity of DNA in the presence of metal ions and the development of a new class of sensors for on-site and real-time detection of metal ions: Applied Inorganic Chemistry Award 2015 Winner: Prof. Yi Lu
2015 04 30 | Parisa Hosseinzadeh has been chosen as a winner of the Robert L. Switzer Award for teaching for this academic year. Congrats!